Zisuva 375/Zisuva 625/Zisuva 1G/Zisuva DS: Zisuva 600/Zisuva 1200: Before initiating therapy with amoxicillin/clavulanic acid, careful enquiry should be made concerning previous hypersensitivity reactions to penicillins, cephalosporins, or other beta-lactam agents.
Convulsions may occur in patients with impaired renal function or in those receiving high doses. Amoxicillin/clavulanic acid should be avoided if infectious mononucleosis is suspected since the occurrence of a morbilliform rash has been associated with this condition following the use of amoxicillin. Concomitant use of allopurinol during treatment with amoxicillin can increase the likelihood of allergic skin reactions.